Buspar - a partial agonist of serotonin and dopamine receptors - it has anxiolytic effect. Unlike benzodiazines buspirone does not suppress psychomotor function, or causes its small suppression; in moderate doses does not exponentiate effect of alcohol. It does not render somnolent, relaxant or antiepileptic effect.
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Buspar Product Description
Buspar is a non-benzodiazepine anxiolytic drug that has antidepressant activity. Buspar tranquilizer is prescribed for adolescents aged 18 and older, adults and elderly patients for the symptomatic treatment of excessive anxiety.
Unlike other anxiolytics, Buspar has no muscle relaxant, hypnotic, sedative and antiepileptic activity. This anxiolytic does not affect psychomotor functions of the body and does not cause drug dependence or withdrawal syndrome.
Anxiolytic effect develops gradually and is evident within 1-2 weeks after starting the therapy. The maximum therapeutic effect is achieved approximately 1 month after Buspar systematic use. Buspar dose is selected individually for each patient taking into account the severity of anxiety disorders and the patient's response to the therapeutic dose.
The recommended starting Buspar dose is 15 mg (5 mg - three times daily). If necessary, the daily dose of Buspar can be increased to 45mg. When treating anxiety with Buspar, the maximum daily dose for adults should not exceed 60 mg. The maximum dose of Buspar for elderly patients is not more than 30mg per day.
When treating anxiety disorders, take into account that the anxiolytic effect develops gradually if Buspar tablets are taken regularly. If you miss a dose, take it as soon as you remember. The patients should skip the missed dose of Buspar if it is time for the next scheduled dose. Take the next dose of Buspar at the scheduled time and do not double the dose.
Clinical studies have shown that food can increase the absorbability of Buspar, but grapefruit juice increases the concentration of anxiolytic drug in plasma. To avoid side effects, the patients are advised to refrain from grapefruit or grapefruit juice during Buspar use. Pay attention that tranquilizer should not be taken occasionally, because the therapeutic effect of Buspar develops when taken regularly and at the same time.
Buspar must be stored at room temperature between 15°C to 30°C in an original container for better protection from light and excessive warmth.
Buspar Safety Information
Patients with impaired renal and hepatic function should use Buspar tranquilizer with caution, in reduced doses and with longer intervals between doses.
Buspar drugs should be combined cautiously with drugs depressing the central nervous system and with other anxiolytics. In the case of co-administration of erythromycin, itraconazole and nefazodone with Buspar, it is recommended to reduce the dose of the tranquilizer not to cause side effects.
Clinical trials have shown that the simultaneous use of MAO inhibitors (MAOIs) with Buspar can lead to an increased blood pressure and occurrence of hypertensive crises. Therefore, it is recommended to avoid the concomitant use of Buspar with MAOIs.
Due to the lack of sufficient data about Buspar safety during pregnancy and breastfeeding, the use of tranquilizer is not recommended in pregnant women and nursing mothers. Throughout the treatment period, the patients are advised to avoid using alcohol when taking Buspar tablets.
The material and information contained in this Buspar review are provided for general information only and should not be used as a basis for making medical decisions without consulting a psychiatrist or other health professional. The online pharmacy disclaims all liability for any direct or indirect damages arising out of or in any way connected with access to or use of information about Buspar and treatment of anxiety disorders.
Buspar Side Effects
Buspar rarely causes undesirable effects. Commonly, they occur at the beginning of treatment and disappear in the dose adjustment of this antianxiety agent. The most common undesirable effects caused by Buspar are nausea, headache, excitement, somnolence and fatigue. Less than 4% of patients stop using Buspar because of CNS disorders, such as nervousness, lightheadedness, as well as a variety of sleep disorders. In rare cases, Buspar may cause dry mouth, numbness, depression, tachycardia or allergic reactions, such as rash.