Actonel, which is risedronate - is prescribed for treatment and prevention of osteoporosis (post-menopausal, caused by corticosteroids), Paget disease. Risedronate binds to substance of a bone tissue, inhibits its resorption mediated by osteoclasts and reduces a bone turn (does not break process of formation of a bone). It increases the biomechanical strength and volume of bone mass. The maximum decrease in a bone turn is observed in 3-6 months, remaining at the same level during a course of treatment.
Arava - a basic medicine with antirheumatic effect. Action is happened due to active metabolite of leflunomid. It has the inhibiting action on degidrorotate-dehydrogenase. Taking the medicine the progression of rheumatoid arthritis is slowed down, it is stopped the affection of arthral layers. Development of therapeutic effect is observed in a month. Increase of effect is noted within half a year.
Evista drug for treatment of osteoporosis. The selection modulator of estrogenic receptors. It has a selective promoting effect at not reproductive tissues and a suppressing effect at reproductive tissues. The biological effect, as well as effect of estrogen, it is mediated by high-affinity linking with oestrogenic receptors and regulation of an expression of genes.